p5.4xlarge


Amazon EC2 instance p5.4xlarge with 16 vCPUs, 256 GiB RAM and 1 x NVIDIA H100 80 GiB. Available in 10 regions starting from $5022.40 per month.
Instance Typep5.4xlarge
Instance FamilyGPU instance
DetailsGPU intensive tasks like machine/deep learning, high-performance computing

p – Performance / GPU (Graphics Processing Unit) accelerated
5 – Generation
4xlarge – Size
vCPUs16
Memory256 GiB
CPU Architecturex86_64
ProcessorAMD EPYC 7R13 Processor
Clock Speed3.6 GHz
Threads Per Core2
Accelerators
GPUyes
GPU NameH100
GPU ManufacturerNVIDIA
GPUs1
GPU Memory80 GiB
GPU Total Memory80 GiB
Inference Acceleratorno
Accelerator Memory803 GiB
FPGAno
Instances
Sizesp5.4xlarge, p5.48xlarge
SageMakerml.p5.4xlarge
Free Tierno
Burstableno
Hibernationno
Instance Storage1 x 3840 GB SSD
EBS (Elastic Block Store)
EBS Optimizeddefault
Encryptionsupported
NVMerequired
Dedicated Throughput10240 MBps
Optimized Baseline Bandwidth10000 Mbps
Optimized Baseline Throughput1250 Mbps
Optimized Baseline Performance32500 IOPS
Optimized Max Performance32500 IOPS
Optimized Max Bandwidth10000 Mbps
Optimized Max Throughput1250 Mbps
Networking
Networking Performance100 Gigabit
Enhanced Networkingyes
Max Interfaces4
Max Cards1
IPv4 Addresses per Interface30
IPv6 Addresses per Interface30
IPv6 Supportyes
ENA Supportrequired
EFA Supportyes
EFA Max Interfaces1
Encryption in Transit Supportyes
ENA SRD Supportyes

Regional Availability

US
GovCloud (US-East) / us-gov-east-1
GovCloud (US-West) / us-gov-west-1
US East (Ohio) / us-east-2
US East (Virginia) / us-east-1
US West (N. California) / us-west-1
US West (Oregon) / us-west-2
Central America
Mexico (Central) / mx-central-1
Canada
Canada (Central) / ca-central-1
Canada West (Calgary) / ca-west-1
Europe
Europe (Ireland) / eu-west-1
Europe (London) / eu-west-2
Europe (Frankfurt) / eu-central-1
Europe (Milan) / eu-south-1
Europe (Paris) / eu-west-3
Europe (Spain) / eu-south-2
Europe (Stockholm) / eu-north-1
Europe (Zurich) / eu-central-2
Africa
Africa (Cape Town) / af-south-1
South America
South America (São Paulo) / sa-east-1
Asia Pacific
Asia Pacific (Hong Kong) / ap-east-1
Asia Pacific (Hyderabad) / ap-south-2
Asia Pacific (Jakarta) / ap-southeast-3
Asia Pacific (Malaysia) / ap-southeast-5
Asia Pacific (Melbourne) / ap-southeast-4
Asia Pacific (Mumbai) / ap-south-1
Asia Pacific (New Zealand) / ap-southeast-6
Asia Pacific (Osaka) / ap-northeast-3
Asia Pacific (Seoul) / ap-northeast-2
Asia Pacific (Singapore) / ap-southeast-1
Asia Pacific (Sydney) / ap-southeast-2
Asia Pacific (Taipei) / ap-east-2
Asia Pacific (Thailand) / ap-southeast-7
Asia Pacific (Tokyo) / ap-northeast-1
Middle East
Israel (Tel Aviv) / il-central-1
Middle East (Bahrain) / me-south-1
Middle East (UAE) / me-central-1

Regional Prices

US Dollar ($)
Per Hour
Linux
Shared Tenancy
On Demand
Geography
Region Name
Region
Savings Options
Instance Price
HiddenHiddenhidden-2compare6.8800
HiddenHiddenhidden-3compare8.2560
HiddenHiddenhidden-4compare8.6000
HiddenHiddenhidden-5compare8.9440
HiddenHiddenhidden-6compare8.9440
HiddenHiddenhidden-7compare11.5584
Asia PacificAsia Pacific (Mumbai)ap-south-1comparen/a
Asia PacificAsia Pacific (Jakarta)ap-southeast-3comparen/a
HiddenHiddenhidden-1comparen/a
USUS East (Virginia)us-east-1comparen/a
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Best AI models you can run on this instance

Top open-weight chat models ranked by Intelligence Index that fit in p5.4xlarge's 80 GB of GPU memory. VRAM is estimated from the parameter count at the selected quantization, so treat it as guidance rather than a guarantee.

Chat Models
FP16 (full precision)
Model
Creator
Intelligence
Total params
Active params
~VRAM
Qwen3.6 27BAlibaba logoAlibaba45.8#5127B—65 GB
Qwen3.5 27BAlibaba logoAlibaba42.1#7127B—65 GB
Gemma 4 31BGoogle logoGoogle39.2#9231B—74 GB
7 more models fit on p5.4xlarge
Unlock the full ranked list and FP8 / INT4 quantization with a CloudPrice subscription.

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